2-Oxohistidine

2-Oxohistidine is a form of histidine damaged by reactive oxygen species. It can serve as a biological marker for assessing protein modifications from oxidative stress.[1]

2-Oxohistidine
Names
IUPAC name
3-(2-Oxo-2H-imidazol-4-yl)alanine
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C6H7N3O3/c7-4(5(10)11)1-3-2-8-6(12)9-3/h2,4H,1,7H2,(H,10,11) COPY
    Key: MWUSZYAURGSGRY-UHFFFAOYSA-N
  • C1=NC(=O)N=C1CC(C(=O)O)N
Properties
C6H7N3O3
Molar mass 169.140 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References
  1. Uchida K, Kawakishi S (1993). "2-Oxo-histidine as a novel biological marker for oxidatively modified proteins". FEBS Lett. 332 (3): 208–210. doi:10.1016/0014-5793(93)80632-5. PMID 8405458.
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