Cis-muuroladiene synthase
Cis-muuroladiene synthase (EC 4.2.3.67, MxpSS1) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cis-muuroladiene-forming).[1] This enzyme catalyses the following chemical reaction
- (1) (2E,6E)-farnesyl diphosphate cis-muurola-3,5-diene + diphosphate
- (2) (2E,6E)-farnesyl diphosphate cis-muurola-4(14),5-diene + diphosphate
| Cis-muuroladiene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.67 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The recombinant enzyme from black peppermint produces a mixture of cis-muurola-3,5-diene and cis-muurola-4(14),5-diene.
References
- Prosser IM, Adams RJ, Beale MH, Hawkins ND, Phillips AL, Pickett JA, Field LM (August 2006). "Cloning and functional characterisation of a cis-muuroladiene synthase from black peppermint (Menthaxpiperita) and direct evidence for a chemotype unable to synthesise farnesene". Phytochemistry. 67 (15): 1564–71. doi:10.1016/j.phytochem.2005.06.012. PMID 16083926.
External links
- Cis-muuroladiene+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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