Defi
Defi may refer to:
- Decentralized finance, an experimental form of finance based on cryptocurrency
 - Defi language
 - Le Défi, a defunct America's Cup syndicate from France
 - Le Défi Media Group, mass media company in Mauritius
 - Défi sportif, disabled multisport event
 - Democratic Federalist Independent, a political party in Belgium
 - 10332 Défi or 10332 Defi (1991 JT1), main belt asteroid discovered in 1991
 
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