Saint Isaac
Saint Isaac may refer to:
People
    
- Isaac, son of Abraham in the Old Testament
 - Saint Isaac of Dalmatia (4th-century–383)
 - Saint Isaac of Monteluco, also called St. Isaac of Spoleto (died c. 550)
 - Saint Isaac Jogues (1607–1646)
 - Saint Isaac of Dafra
 - Saint Isaac of Armenia (338–439)
 - Saint Isaac of Nineveh (died c. 700)
 
Buildings, structures, and places
    
- Saint Isaac's Cathedral, in Saint Petersburg, Russia
 - Saint Isaac's Square, in Saint Petersburg, Russia
 - Saint Isaac's Bridge, the first bridge across Neva river in St.Petersburg, Russia
 
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