N-acylneuraminate-9-phosphatase
In enzymology, a N-acylneuraminate-9-phosphatase (EC 3.1.3.29) is an enzyme that catalyzes the chemical reaction
- N-acylneuraminate 9-phosphate + H2O N-acylneuraminate + phosphate
| N-acylneuraminate-9-phosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 N-acylneuraminate-9-phosphatase homodimer, Human | |||||||||
| Identifiers | |||||||||
| EC no. | 3.1.3.29 | ||||||||
| CAS no. | 37288-13-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are N-acylneuraminate 9-phosphate and H2O, whereas its two products are N-acylneuraminate and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is N-acylneuraminate-9-phosphate phosphohydrolase. Other names in common use include acylneuraminate 9-phosphatase, N-acylneuraminic acid 9-phosphate phosphatase, and N-acylneuraminic (sialic) acid 9-phosphatase. This enzyme participates in aminosugars metabolism.
References
- Jourdian GW, Swanson A, Watson D, Roseman S (1966). "N-Acetylneuraminic (sialic) acid 9-phosphatase". Methods Enzymol. 8: 205–208. doi:10.1016/0076-6879(66)08034-0.
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