2018 US Open – Wheelchair men's singles
Stéphane Houdet was the defending champion, but lost to Nicolas Peifer in the quarterfinals.
| Wheelchair men's singles | |
|---|---|
| 2018 US Open | |
| Champion | |
| Runner-up | |
| Final score | 6–3, 7–5 | 
Alfie Hewett won his first title, defeating Shingo Kunieda in the final, 6–3, 7–5.
Seeds
    
 Shingo Kunieda (final)
 Alfie Hewett (champion)
Draw
    
    Key
    
- Q = Qualifier
 - WC = Wild card
 - LL = Lucky loser
 - Alt = Alternate
 - SE = Special exempt
 - PR = Protected ranking
 - ITF = ITF entry
 - JE = Junior exempt
 - w/o = Walkover
 - r = Retired
 - d = Defaulted
 - SR = Special ranking
 
Bracket
    
| Quarterfinals | Semifinals | Final | ||||||||||||||||||
| 1 | 0 | 6 | 6 | |||||||||||||||||
| 6 | 1 | 3 | ||||||||||||||||||
| 1 | 2 | 6 | 7 | |||||||||||||||||
| WC | 6 | 4 | 5 | |||||||||||||||||
| 2 | 2 | |||||||||||||||||||
| WC | 6 | 6 | ||||||||||||||||||
| 1 | 3 | 5 | ||||||||||||||||||
| 2 | 6 | 7 | ||||||||||||||||||
| 1 | 4 | |||||||||||||||||||
| 6 | 6 | |||||||||||||||||||
| 62 | 1 | |||||||||||||||||||
| 2 | 77 | 6 | ||||||||||||||||||
| 5 | 4 | |||||||||||||||||||
| 2 | 7 | 6 | ||||||||||||||||||
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