Collagen, type XXI, alpha 1

COL21A1
Identifiers
Aliases	COL21A1, collagen, type XXI, alpha 1, COLA1L, dJ682J15.1, dJ708F5.1, FP633, collagen type XXI alpha 1, collagen type XXI alpha 1 chain
External IDs	OMIM: 610002 HomoloGene: 49949 GeneCards: COL21A1
Gene location (Human)
Chr.	Chromosome 6 (human)[1]
End	56,394,094 bp[1]
RNA expression pattern
	Top expressed in
	heart; ; stomach; ; kidney; ; sural nerve; ; lung; ; myocardium; ; colon; ; thoracic aorta;
	More reference expression data
	n/a
Gene ontology
Molecular function	extracellular matrix structural constituent conferring tensile strength;
Cellular component	cytoplasm; GO:0005578 extracellular matrix; extracellular region; collagen trimer; endoplasmic reticulum lumen; cytosol; extracellular space; collagen-containing extracellular matrix;
Biological process	growth plate cartilage chondrocyte morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	81578
	n/a
	ENSG00000124749
	n/a
	Q96P44
	n/a
	NM_030820; NM_001318751; NM_001318752; NM_001318753; NM_001318754
	n/a
	NP_001305680; NP_001305681; NP_001305682; NP_001305683; NP_110447
	n/a
	Wikidata
View/Edit Human

Collagen alpha-1(XXI) chain is a protein that in humans is encoded by the COL21A1 gene.[3] The protein is an extracellular matrix component of blood vessel walls, secreted by smooth-muscle cells. The protein may contribute to the extracellular matrix assembly of the vascular network during blood vessel formation.[4]

References

GRCh38: Ensembl release 89: ENSG00000124749 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"COL21A1 collagen, type XXI, alpha 1". Entrez Gene: COL21A1. United States National Center for Biotechnology Information.
Chou MY, Li HC (March 2002). "Genomic organization and characterization of the human type XXI collagen (COL21A1) gene". Genomics. 79 (3): 395–401. doi:10.1006/geno.2002.6712. PMID 11863369.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000124749 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "COL21A1 collagen, type XXI, alpha 1". Entrez Gene: COL21A1. United States National Center for Biotechnology Information.

[4] Chou MY, Li HC (March 2002). "Genomic organization and characterization of the human type XXI collagen (COL21A1) gene". Genomics. 79 (3): 395–401. doi:10.1006/geno.2002.6712. PMID 11863369.