CXCL15

Chemokine (C-X-C motif) ligand 15 (CXCL15) is a small cytokine belonging to the CXC chemokine family that has been described in the mouse. This chemokine is also known under the name lungkine. CXCL15 is an ELR+ CXC chemokine (it contains the amino acid sequence E-L-R immediately before its CXC motif) that recruits neutrophils during inflammation of the lungs. It is highly abundant in epithelial cells of the lung,[2] and can also be found in other mucosal organs such as the urogenital and gastrointestinal tracts, and in endocrine organs like the adrenal gland.[3] The gene for CXCL15 is found on mouse chromosome 5.

Cxcl15
Identifiers
Aliases	chemokine (C-X-C motif) ligand 15Il8Scyb15lungkineweche
External IDs	GeneCards:
Gene location (Human) Chr. Chromosome 5 (human) Band 5 E1|5 44.78 cM Start 90,942,393 bp End 90,950,926 bp
Gene ontology Molecular function chemokine activity cytokine activity CXCR3 chemokine receptor binding Cellular component extracellular region extracellular space Biological process chemotaxis chemokine-mediated signaling pathway G protein-coupled receptor signaling pathway response to lipopolysaccharide inflammatory response regulation of cell population proliferation immune response neutrophil chemotaxis positive regulation of leukocyte chemotaxis defense response T cell chemotaxis regulation of signaling receptor activity hemopoiesis leukocyte chemotaxis antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	20309	n/a
Ensembl	ENSMUSG00000029375	n/a
UniProt	Q9WVL7	n/a
RefSeq (mRNA)	NM_011339	n/a
RefSeq (protein)	NP_035469	n/a
Location (UCSC)	Chr 5: 90.94 – 90.95 Mb	n/a
PubMed search	[1]	n/a
Wikidata
View/Edit Human