Flurithromycin

Flurithromycin is a macrolide antibiotic. It is a fluorinated derivative of erythromycin A.[1]

Flurithromycin
Clinical data
ATC code
Identifiers
  • (3R,4S,5S,6R,7R,9S,11R,12R,13S,14R)-6-
    [(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-
    6-methyloxan-2-yl]oxy-14-ethyl-9-fluoro-7,12,
    13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-
    4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,
    11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.126.548
Chemical and physical data
FormulaC37H66FNO13
Molar mass751.927 g·mol−1
3D model (JSmol)
  • O=C3O[C@H](CC)[C@](O)(C)[C@H](O)[C@H](C(=O)[C@](F)(C)C[C@](O)(C)[C@H](O[C@@H]1O[C@H](C)C[C@H](N(C)C)[C@H]1O)[C@H]([C@H](O[C@@H]2O[C@H]([C@H](O)[C@](OC)(C2)C)C)[C@H]3C)C)C
  • InChI=1S/C37H66FNO13/c1-14-24-37(10,46)29(42)21(5)28(41)34(7,38)17-35(8,45)31(52-33-26(40)23(39(11)12)15-18(2)48-33)19(3)27(20(4)32(44)50-24)51-25-16-36(9,47-13)30(43)22(6)49-25/h18-27,29-31,33,40,42-43,45-46H,14-17H2,1-13H3/t18-,19+,20-,21+,22+,23+,24-,25+,26-,27+,29-,30+,31-,33+,34+,35-,36-,37-/m1/s1 Y
  • Key:XOEUHCONYHZURQ-HNUBZJOYSA-N Y
 NY (what is this?)  (verify)

References
  1. Gialdroni Grassi G, Alesina R, Bersani C, Ferrara A, Fietta A, Peona V (June 1986). "In vitro activity of flurithromycin, a novel macrolide antibiotic". Chemioterapia : International Journal of the Mediterranean Society of Chemotherapy. 5 (3): 177–84. PMID 3487389.


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