Serratia marcescens nuclease
Serratia marcescens nuclease (EC 3.1.30.2, endonuclease (Serratia marcescens), barley nuclease, plant nuclease I, nucleate endonuclease) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction
- Endonucleolytic cleavage to 5'-phosphomononucleotide and 5'-phosphooligonucleotide end-products
| Serratia marcescens nuclease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.30.2 | ||||||||
| CAS no. | 9025-65-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
| Serratia marcescens nuclease | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Organism | |||||||
| Symbol | nucA | ||||||
| UniProt | P13717 | ||||||
| |||||||
Hydrolyses double- or single-stranded substrate. It is a representative of the DNA/RNA non-specific endonuclease family.
References
- Mikulski AJ, Laskowski M (October 1970). "Mung bean nuclease I. 3. Purification procedure and (3') omega monophosphatase activity". The Journal of Biological Chemistry. 245 (19): 5026–31. PMID 4319109.
- Stevens, A.; Hilmoe, R.J. (1960). "Studies on a nuclease from Azotobacter agilis. I. Isolation and mode of action". J. Biol. Chem. 235: 3016–3022.
- Stevens A, Hilmoe RJ (1960). "Studies on a nuclease from Azotobacter agilis. II. Hydrolysis of ribonucleic and deoxyribonucleic acids". J. Biol. Chem. 235: 3023–3027.
- Wechter WJ, Mikulski AJ, Laskowski M (February 1968). "Gradation of specificity with regard to sugar among nucleases". Biochemical and Biophysical Research Communications. 30 (3): 318–22. doi:10.1016/0006-291x(68)90453-1. PMID 4296679.
External links
- Serratia+marcescens+nuclease at the US National Library of Medicine Medical Subject Headings (MeSH)
- Serratia marcescens endonuclease at Protean Ltd., highly active
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.