Tramazoline

Tramazoline is a chemical that is used in the form of tramazoline hydrochloride in nasal decongestant preparations.[1] It is an α-adrenergic receptor agonist that inhibits secretion of nasal mucus.

Tramazoline
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.012.823
Chemical and physical data
FormulaC13H17N3
Molar mass215.300 g·mol−1
 NY (what is this?)  (verify)

It was patented in 1961 and came into medical use in 1962.[2]

Brand names
  • Australia
    • Spray-Tish[3]
    • Rhinaspray
  • Austria
    • Rhinorix
  • Belgium
    • Rhinospray
  • Bulgaria
    • Muconasal Plus
  • Czech Republic
    • Muconasal Plus
  • Germany
    • Biciron
    • Ellatun
    • Rhinospray
  • Hungary
    • Rhinospray Plus
  • Italy
    • Rinogutt
    • Fexallegra nasale (Tramazoline + Chlorpheniramine, 1 mg/ml + 3.55 mg/ml)
  • Portugal
    • Rhinospray
  • Romania
    • Muconasal Plus (older)
    • Muconasal (newer)
  • Russia
  • Spain
    • Rhinospray
  • Slovakia
    • Muconasal Plus
  • Ukraine
    • Lasorin
  • US

References
  1. "Spray-Tish Consumer Information". MyDr.com.au. Retrieved 16 April 2011.
  2. Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 552. ISBN 9783527607495.
  3. "Consumer medicine information: Spray-Tish". nps.org.au. NPS MedicineWise. Retrieved September 13, 2021.
  4. "Trama". Consumer Information. Retrieved 21 December 2019.


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