Felbinac

Felbinac (INN, or biphenylylacetic acid) is a topical medicine,[1] belonging to the family of medicines known as nonsteroidal anti-inflammatory drugs (NSAIDs) of the arylacetic acid (not arylpropionic acid) class, which is used to treat muscle inflammation and arthritis.[2] It is an active metabolite of fenbufen.[3]

Felbinac
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Topical
ATC code
Legal status
Legal status
Identifiers
  • biphenyl-4-ylacetic acid
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.024.758
Chemical and physical data
FormulaC14H12O2
Molar mass212.248 g·mol−1
3D model (JSmol)
  • O=C(O)Cc1ccc(cc1)c2ccccc2
  • InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16) Y
  • Key:QRZAKQDHEVVFRX-UHFFFAOYSA-N Y
  (verify)

The α-methyl acid of felbinac is called biprofen and is used to prepare bifepramide. The α-ethyl acid is called xenbucin which is used to make xenthiorate.

See also

References
  1. The Merck Index, 12th Edition. 3989
  2. Description of Felbinac on Tiscali
  3. Kohler C, Tolman E, Wooding W, Ellenbogen L (1980). "A review of the effects of fenbufen and a metabolite, biphenylacetic acid, on platelet biochemistry and function". Arzneimittelforschung. 30 (4A): 702–707. PMID 6254545.


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