Lithium citrate

Lithium citrate (Li3C6H5O7) is a chemical compound of lithium and citrate that is used as a mood stabilizer in psychiatric treatment of manic states and bipolar disorder.[1][2] There is extensive pharmacology of lithium, the active component of this salt.

Lithium citrate
Names
Other names
Trilithium citrate
trilithium 2-hydroxypropane-1,2,3-tricarboxylate
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.011.860
EC Number
  • 213-045-8
RTECS number
  • TZ8616000
UNII
  • InChI=1S/C6H8O7.3Li/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3 Y
    Key: WJSIUCDMWSDDCE-UHFFFAOYSA-K Y
  • InChI=1/C6H8O7.3Li/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3
    Key: WJSIUCDMWSDDCE-DFZHHIFOAV
  • [Li+].[Li+].[Li+].O=C([O-])CC(O)(C([O-])=O)CC(=O)[O-]
Properties
Li3C6H5O7
Molar mass 209.923 g mol−1
Appearance Odorless white powder
Melting point decomposes at 105 °C (221 °F; 378 K)
Hazards
GHS labelling:
Warning
H302, H319
P305+P351+P338
Flash point N/A
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Lithia water contains various lithium salts, including the citrate. An early version of Coca-Cola available in pharmacies' soda fountains called Lithia Coke was a mixture of Coca-Cola syrup and lithia water. The soft drink 7Up was originally named "Bib-Label Lithiated Lemon-Lime Soda" when it was formulated in 1929 because it contained lithium citrate. The beverage was a patent medicine marketed as a cure for hangover. Lithium citrate was removed from 7Up in 1948.[3]

References
  1. Medication description
  2. Medical use Archived 2006-06-15 at the Wayback Machine
  3. Gielen, Marcel; Edward R. T. Tiekink (2005). Metallotherapeutic drugs and metal-based diagnostic agents: The use of metals in medicine. John Wiley and Sons. p. 3. ISBN 0-470-86403-6.


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